Collection: REG-ulate360 Complex™

REG-ulate360 Complex™ is the proprietary antioxidant complex at the heart of every Dr. Zenovia formula — developed by board-certified dermatologist Dr. Zenovia Gabriel, MD to calm redness, defend against environmental stress, and support the skin barrier while each product's clinical active does its job. It's what lets the line work in concert across acne, aging, sensitivity, and tone.

What is REG-ulate360 Complex™?

REG-ulate360 Complex™ is a proprietary blend of medical-grade actives — Resveratrol, Vitamin E, Green Tea polyphenols, Bakuchiol, and Genistein, a plant-derived antioxidant. Together they help calm visible redness, neutralize the free radicals that accelerate visible aging, and support a strong, resilient barrier, so skin looks clearer, calmer, and more even.

Why did a dermatologist develop it?

In practice, Dr. Zenovia saw the same pattern in patients at every stage of life, from puberty to pregnancy to menopause: skin that responds to stress with breakouts, redness, dryness, and faster aging. Most skincare treated one symptom at a time. She built REG-ulate360 Complex™ so every step of a routine also calms inflammation and protects the barrier, not just the treatment step. It's clinical skincare informed by real dermatology.

What does REG-ulate360 Complex™ do for your skin?

• Calms visible redness and reactivity, supporting a clear, even complexion.
• Delivers antioxidant protection against the free-radical and environmental damage that accelerate aging.
• Supports the skin barrier for healthier, more resilient skin.
• Works across concerns — the unifying technology behind Dr. Zenovia's acne, anti-aging, sensitivity, and brightening formulas.

Which products contain REG-ulate360 Complex™?

It's the through-line of the entire collection — you'll find REG-ulate360 Complex™ in Dr. Zenovia's cleansers, toners, serums, moisturizers, treatments, eye care, and SPF. That's by design: every step of your routine works toward the same goal of calm, balanced, healthy-looking skin.

Frequently asked questions about REG-ulate360 Complex™

What is REG-ulate360 Complex™?
Dr. Zenovia's proprietary blend of Resveratrol, Vitamin E, Green Tea polyphenols, Bakuchiol, and the plant-derived antioxidant Genistein, designed to calm redness and protect the skin barrier alongside each product's clinical active.

What is Genistein and why is it in the formula?
Genistein is a plant-derived antioxidant (an isoflavone found in soy). It's included for its calming, antioxidant effect at the skin's surface; it works topically and is not absorbed systemically.

Is REG-ulate360 Complex™ safe for sensitive skin?
Yes. Every Dr. Zenovia formula featuring the complex is developed for sensitive skin, with a focus on being effective yet gentle.

Do I need a specific skin concern to benefit from it?
No. Its antioxidant protection and barrier support benefit all skin types and concerns.

What makes REG-ulate360 Complex™ different from other skincare ingredients?
It's a dermatologist-developed technology built around how skin responds to inflammation and stress — the common thread behind acne, sensitivity, and aging — and it's the clinical foundation that unifies the entire Dr. Zenovia line.

Developed by board-certified dermatologist Dr. Zenovia Gabriel — clinical skincare rooted in the science of healthy skin.