Collection: REG-ulate360 Complex™

REG-ulate360 Complex™ is the proprietary technology at the heart of every Dr. Zenovia formula — developed by board-certified dermatologist Dr. Zenovia Gabriel to address one of the most overlooked drivers of skin concerns: hormonal change. It's what makes this line clinically distinct, and it's the reason the products work in concert across acne, aging, sensitivity, and tone.

What is REG-ulate360 Complex™?

REG-ulate360 Complex™ is a proprietary blend of medical-grade actives — including Resveratrol, Vitamin E, Green Tea polyphenols, and Genistein, a cutting-edge plant-derived phytoestrogen. Together, these ingredients help restore the appearance of skin affected by hormonal changes to an optimal, healthy state, while delivering powerful antioxidant protection and supporting the skin barrier.

Why did a dermatologist develop it?

Throughout her years in clinical practice, Dr. Zenovia saw how profoundly hormonal shifts — from puberty and menstrual cycles to pregnancy and menopause — affect the skin, triggering everything from breakouts to dryness, sensitivity, and accelerated aging. Yet most skincare ignored this entirely. She developed REG-ulate360 Complex™ to address skin through this lens: not just treating symptoms on the surface, but supporting skin as it navigates hormonal change. It's clinical skincare informed by real dermatology.

What does REG-ulate360 Complex™ do for your skin?

• Helps rebalance the look of skin affected by hormonal changes, supporting a healthy, clear, even complexion.
• Delivers antioxidant protection against the free-radical and environmental damage that accelerate aging.
• Supports the skin barrier for healthier, more resilient skin.
• Works across concerns — the unifying technology behind Dr. Zenovia's acne, anti-aging, sensitivity, and brightening formulas.

Which products contain REG-ulate360 Complex™?

It's the through-line of the entire collection — you'll find REG-ulate360 Complex™ in Dr. Zenovia's cleansers, toners, serums, moisturizers, treatments, eye care, and SPF. That's by design: it means every step of your routine is working toward the same goal of balanced, healthy-looking skin.

Frequently asked questions about REG-ulate360 Complex™

What is REG-ulate360 Complex™?
It's Dr. Zenovia's proprietary blend of medical-grade actives — Resveratrol, Vitamin E, Green Tea, and the plant-derived phytoestrogen Genistein — designed to help restore the appearance of skin affected by hormonal changes while providing antioxidant protection and barrier support.

What is Genistein and why is it in the formula?
Genistein is a plant-derived phytoestrogen — a botanical compound included to help support skin as it responds to hormonal changes. It's a key part of what makes REG-ulate360 Complex™ distinct.

Is REG-ulate360 Complex™ safe for sensitive skin?
Yes. Every Dr. Zenovia formula featuring the complex is developed for sensitive skin, with a focus on being effective yet gentle.

Do I need hormonal skin concerns to benefit from it?
No. While REG-ulate360 Complex™ is especially valuable for skin navigating hormonal change, its antioxidant protection and barrier support benefit all skin types and concerns.

What makes REG-ulate360 Complex™ different from other skincare ingredients?
It's a proprietary, dermatologist-developed technology built specifically around how hormones affect the skin — a perspective most skincare overlooks. It's the clinical foundation that unifies the entire Dr. Zenovia line.

Developed by board-certified dermatologist Dr. Zenovia Gabriel — clinical skincare rooted in the science of healthy skin.